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    Dexilant 60 Mg - 28 Caps

    SKU: Z.49723.17144025687579045
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    SAR 98.95

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    Description

    Dexilant 60 Mg, Reduce Stomach Acidity & Relief Heartburn - 28 Capsules

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    Product Details

    Product Name

    • Dexilant 60 Mg, Reduce Stomach Acidity & Relief Heartburn - 28 Capsules

    Scientific Name

    • Dexlansoprazole 60 Mg Capsules

     

    Category Of Dexilant 60 Mg Capsules

    • Heartburn Drugs

    Mechanism Of Action Of Dexlansoprazole

    • Hydrochloric acid (HCl) secretion into the gastric lumen is a process regulated mainly by the H (+)/K (+)-ATPase of the proton pump, expressed in high quantities by the parietal cells of the stomach.
    • proton pump inhibitor that inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium (H+/K+-exchanging ATPase), the “proton pump” of the gastric parietal cell.
    • Dexlansoprazole is a member of a class called “proton pump inhibitors”

    Therapeutic Indications Of Dexilant 60 Mg Capsules

    • Duodenal ulcers (a sore that forms at the beginning of your small intestine)
    • H Pylori eradication (bacteria that can live in your gut and cause ulcers) to prevent recurrence of duodenal ulcers
    • Benign gastric ulcer (a non-cancerous sore that forms in your stomach)
    • NSAID-associated ulcer (sore that forms in your gut due to excessive use of NSAIDs)
    • GERD (acid reflux also known as “heartburn”): is the backflow of acid from the stomach into the gullet (“food pipe”) which may become inflamed and painful. This may cause your symptoms such as a painful sensation in the chest rising to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
    • Erosive esophagitis (acid irritation injuring the esophagus): inflammation that may damage tissues of the esophagus, the muscular tube that delivers food from your mouth to your stomach. Esophagitis can cause painful, difficult swallowing and chest pain.
    • Pathological hyper-secretory conditions (problems in the gut that cause excessive acid production)

    Method Of Administration Of Dexilant 60 Mg Capsules

    • Take with or without food
    • Swallow whole; do not chew
    • Healing of erosive esophagitis: 60 mg once daily for up to 8 weeks
    • Maintenance of healed erosive esophagitis: 30 mg once daily for up to 6 months
    • Symptomatic non-erosive GERD: 30 mg once daily for 4 weeks
    • Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
    • If you take more than you should, talk to a doctor or go to the hospital straight away.
    • If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
    • Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

     

    Undesirable Side Effects Of Dexilant 60 Mg Capsules

    • Most commonly reported adverse reactions (≥2%): diarrhea, abdominal pain, nausea, upper respiratory tract infection, vomiting, and flatulence.

     

    Pregnancy & Breastfeeding Precautions While Taking Dexilant 60 Mg Capsules

    • If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

    Non-Pharmacological Treatments & Advice To Reduce Heartburn

    • Eat sparingly and slowly
    • Avoid certain foods like (Fried food, Chili foods, …etc.)
    • Don't drink carbonated beverages
    • Stay up after eating & Finish eating three hours before you go to bed
    • Don't move too fast
    • Sleep on an incline
    • Lose weight if it's advised
    • Avoid tight clothes
    • If you smoke, quit
    • Remember you can always check for H-Pylori Infection by using Heli C Check, H. Pylori Self-Testing Device

     

    Warnings & Special Precautions While Taking Dexilant 60 Mg Capsules

    • Do not use this medication in:
    1. Patients with known hypersensitivity to any component of the formulation
    2. Patients receiving rilpivirine-containing products
    • Gastric Malignancy: Symptomatic response with dexlansoprazole does not preclude the presence of gastric malignancy
    • Acute Interstitial Nephritis: Observed in patients taking PPIs
    • Cyanocobalamin (Vitamin B-12) Deficiency: Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin
    • Clostridium difficile Associated Diarrhea: PPI therapy may be associated with increased risk
    • Bone Fracture: Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine
    • Hypomagnesemia: Reported rarely with prolonged treatment with PPIs
    • Interactions with Diagnostic Investigations for Neuroendocrine Tumors: Increases in intragastric pH may result in hypergastrinemia and enterochromaffin-like cell hyperplasia and increased
    • chromogranin A levels which may interfere with diagnostic investigations for neuroendocrine tumors
    • Interaction with Methotrexate: Concomitant use with PPIs may elevate and/or prolong serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal.
    • Tell your doctor or pharmacist if you are taking:
    1. Antiretrovirals
    2. Warfarin
    3. Methotrexate
    4. Digoxin
    5. Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib,
    6. mycophenoloate mofetil, ketoconazole/itraconazole)
    7. Tacrolimus
    8. CYP2C19 or CYP3A4 Inhibitors
    9. CYP2C19 or CYP3A4 Inducers

     

    Storage Conditions Of Dexilant 60 Mg Capsules

    • Store below 25°c
    • Don’t refrigerate
    • Keep this medicine out of the sight and reach of children.
    • Store in the original package to protect from moisture.
    • Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.

    Product Name

    • Dexilant 60 Mg, Reduce Stomach Acidity & Relief Heartburn - 28 Capsules

    Scientific Name

    • Dexlansoprazole 60 Mg Capsules

     

    Category Of Dexilant 60 Mg Capsules

    • Heartburn Drugs

    Mechanism Of Action Of Dexlansoprazole

    • Hydrochloric acid (HCl) secretion into the gastric lumen is a process regulated mainly by the H (+)/K (+)-ATPase of the proton pump, expressed in high quantities by the parietal cells of the stomach.
    • proton pump inhibitor that inhibits the secretion of gastric acid by irreversibly blocking the enzyme system of hydrogen/potassium (H+/K+-exchanging ATPase), the “proton pump” of the gastric parietal cell.
    • Dexlansoprazole is a member of a class called “proton pump inhibitors”

    Therapeutic Indications Of Dexilant 60 Mg Capsules

    • Duodenal ulcers (a sore that forms at the beginning of your small intestine)
    • H Pylori eradication (bacteria that can live in your gut and cause ulcers) to prevent recurrence of duodenal ulcers
    • Benign gastric ulcer (a non-cancerous sore that forms in your stomach)
    • NSAID-associated ulcer (sore that forms in your gut due to excessive use of NSAIDs)
    • GERD (acid reflux also known as “heartburn”): is the backflow of acid from the stomach into the gullet (“food pipe”) which may become inflamed and painful. This may cause your symptoms such as a painful sensation in the chest rising to your throat (heartburn) and a sour taste in the mouth (acid regurgitation).
    • Erosive esophagitis (acid irritation injuring the esophagus): inflammation that may damage tissues of the esophagus, the muscular tube that delivers food from your mouth to your stomach. Esophagitis can cause painful, difficult swallowing and chest pain.
    • Pathological hyper-secretory conditions (problems in the gut that cause excessive acid production)

    Method Of Administration Of Dexilant 60 Mg Capsules

    • Take with or without food
    • Swallow whole; do not chew
    • Healing of erosive esophagitis: 60 mg once daily for up to 8 weeks
    • Maintenance of healed erosive esophagitis: 30 mg once daily for up to 6 months
    • Symptomatic non-erosive GERD: 30 mg once daily for 4 weeks
    • Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
    • If you take more than you should, talk to a doctor or go to the hospital straight away.
    • If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
    • Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

     

    Undesirable Side Effects Of Dexilant 60 Mg Capsules

    • Most commonly reported adverse reactions (≥2%): diarrhea, abdominal pain, nausea, upper respiratory tract infection, vomiting, and flatulence.

     

    Pregnancy & Breastfeeding Precautions While Taking Dexilant 60 Mg Capsules

    • If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

    Non-Pharmacological Treatments & Advice To Reduce Heartburn

    • Eat sparingly and slowly
    • Avoid certain foods like (Fried food, Chili foods, …etc.)
    • Don't drink carbonated beverages
    • Stay up after eating & Finish eating three hours before you go to bed
    • Don't move too fast
    • Sleep on an incline
    • Lose weight if it's advised
    • Avoid tight clothes
    • If you smoke, quit
    • Remember you can always check for H-Pylori Infection by using Heli C Check, H. Pylori Self-Testing Device

     

    Warnings & Special Precautions While Taking Dexilant 60 Mg Capsules

    • Do not use this medication in:
    1. Patients with known hypersensitivity to any component of the formulation
    2. Patients receiving rilpivirine-containing products
    • Gastric Malignancy: Symptomatic response with dexlansoprazole does not preclude the presence of gastric malignancy
    • Acute Interstitial Nephritis: Observed in patients taking PPIs
    • Cyanocobalamin (Vitamin B-12) Deficiency: Daily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalamin
    • Clostridium difficile Associated Diarrhea: PPI therapy may be associated with increased risk
    • Bone Fracture: Long-term and multiple daily dose PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine
    • Hypomagnesemia: Reported rarely with prolonged treatment with PPIs
    • Interactions with Diagnostic Investigations for Neuroendocrine Tumors: Increases in intragastric pH may result in hypergastrinemia and enterochromaffin-like cell hyperplasia and increased
    • chromogranin A levels which may interfere with diagnostic investigations for neuroendocrine tumors
    • Interaction with Methotrexate: Concomitant use with PPIs may elevate and/or prolong serum concentrations of methotrexate and/or its metabolite, possibly leading to toxicity. With high dose methotrexate administration, consider a temporary withdrawal.
    • Tell your doctor or pharmacist if you are taking:
    1. Antiretrovirals
    2. Warfarin
    3. Methotrexate
    4. Digoxin
    5. Drugs Dependent on Gastric pH for Absorption (e.g., iron salts, erlotinib, dasatinib, nilotinib,
    6. mycophenoloate mofetil, ketoconazole/itraconazole)
    7. Tacrolimus
    8. CYP2C19 or CYP3A4 Inhibitors
    9. CYP2C19 or CYP3A4 Inducers

     

    Storage Conditions Of Dexilant 60 Mg Capsules

    • Store below 25°c
    • Don’t refrigerate
    • Keep this medicine out of the sight and reach of children.
    • Store in the original package to protect from moisture.
    • Do not use this medicine after the expiry date which is stated on the box/blisters/label. The expiry date refers to the last day of the month.
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