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Normega … Nutrition for the Heart, Mind, and Body In a world increasingly filled with stress, poor nutrition, and lack of physical activity, maintaining heart and brain health has become a necessity rather than a luxury.
NORMEGA 1000High-Purity Omega-3 For Advanced Lipid ManagementEACH 2 SOFTGEL CAPSULES CONTAIN:EPA 660 mgDHA 440 mgRECOMMENDED DOSAGEMild to Moderate Hypertriglyceridemia(TG 150–499 mg/dL)1–2 g/day(2–4 softgels)Severe Hypertriglyceridemia(TG ≥ 500 mg/dL)2–4 g/day(4–8 softgels)Use as adjunct to diet, exercise, and statin therapy when appropriate.INDICATIONSHypertriglyceridemiaMixed DyslipidemiaCardiovascular Risk ReductionMetabolic SyndromeSAFETY PROFILEGenerally well toleratedMild GI symptoms (e.g., fishy aftertaste, dyspepsia) in some patientsNo significant increase in bleeding risk in clinical studiesNo clinically relevant drug interactionsSuitable for long-term useQuality FeaturesHigh PurityMolecularly DistilledHeavy Metal TestedIFOS CompliantOxidation ControlledMECHANISM OF ACTIONDecreases hepatic VLDL-TG synthesis by reducing substrate availabilityInhibits diacylglycerol acyltransferase (DGAT) and apo-CIII expressionEnhances fatty acid β-oxidation and reduces hepatic steatosisReduces VLDL secretion and plasma triglyceride levelsAnti-inflammatory effects via reduction of cytokines (IL-6, TNF-α, CRP)CLINICAL EVIDENCEMARINE TrialHypertriglyceridemia (TG > 500 mg/dL)n = 229TG Reduction: 33% with 4 g/day Omega-3 (EPA+DHA)ANCHOR TrialTG (200–499 mg/dL) on statin therapyn = 4448TG Reduction: 21.5% with 4 g/day Omega-3 (EPA+DHA)
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