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    Lotevan 10/ 160 mg Tablet 30

    SKU: PrescriptionMedicines_0538
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    Description

    Amlodipine/Valsartan tablets contain two substances called amlodipine and valsartan. These two substances help control high blood pressure.

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    Product Description
    A valid prescription must be presented upon receipt of the order.
     
    What is amlodipine/valsartan and what is it used for?
    Amlodipine/Valsartan tablets contain two substances called amlodipine and valsartan. These two substances help control high blood pressure.
    Amlodipine belongs to a group of substances called "calcium channel blockers". Amlodipine prevents calcium from moving into the blood vessel wall, which prevents the blood vessels from narrowing.
    Valsartan belongs to a group of substances called "angiotensin II receptor antagonists". The body produces angiotensin II and makes the blood vessels narrow, thus increasing blood pressure. Valsartan works by blocking the effect of angiotensin II.
    This means that both of these substances help stop the tightening of blood vessels. As a result, blood vessels relax and blood pressure drops.
    Amlodipine/valsartan is used to treat high blood pressure in adults whose blood pressure is not adequately controlled with amlodipine or valsartan alone.
     
    What you should know before taking amlodipine/valsartan?
    Do not take amlodipine/valsartan:
    • If you are allergic to amlodipine or any other calcium channel blocker. This may include itching, redness of the skin, or trouble breathing.
    • If you are allergic to valsartan or any of the other ingredients of this medicine. If you think you may be allergic, talk to your doctor before taking amlodipine/valsartan.
    • If you suffer from serious liver problems or bile problems such as cirrhosis of the liver or cholestasis.
    • If you are more than 3 months pregnant. (It is also best to avoid amlodipine/valsartan in early pregnancy.)
    • If you suffer from a severe drop in blood pressure (hypotension).
    • If you have narrowing of the aortic valve (aortic stenosis) or cardiogenic shock (a condition in which your heart is unable to supply the body with enough blood).
    • If you suffer from heart failure after a heart attack.
    • If you suffer from diabetes or poor kidney function and are being treated with a medicine to lower blood pressure that contains aliskiren.
     
    Warnings and precautions:
    Talk to your doctor before taking amlodipine/valsartan:
    • If you are sick (vomiting or diarrhoea).
    • If you suffer from liver or kidney problems.
    • If you have had a kidney transplant or if you have been told you have narrowed kidney arteries.
    • If you have a condition affecting the renal glands called "primary hyperaldosteronism".
    • If you suffer from heart failure or a heart attack. Follow your doctor"s instructions for the starting dose carefully. Your doctor may also check your kidney function.
    • If your doctor tells you that you have narrowing of the valves in your heart (called "aortic stenosis or mitral valve") or that the heart muscle is abnormally thickened (called "hypertrophic obstructive cardiomyopathy").
    • If you experience swelling, especially of the face and throat, while taking other medicines (including ACE inhibitors). If you develop these symptoms, stop taking amlodipine/valsartan and call your doctor at once. You should not take amlodipine/valsartan again.
     
    If you are taking any of the following medicines used to treat high blood pressure:
    • ACE inhibitors (eg enalapril, lisinopril, ramipril), especially if you have diabetes-related kidney problems.
    • Aliskiren.
     
    Children and teens:
     
    Amlodipine/valsartan is not recommended for use in children and adolescents (under 18 years of age).
     
    Other medicines and amlodipine/valsartan:
    Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Your doctor may need to change your dose and/or take other precautions. In some cases, you may have to stop taking one of the medicines. This is especially true for the medicines listed below:
    • Angiotensin converting enzyme inhibitors or aliskiren
    Diuretics (a type of medicine also called "water tablets" that increase the amount of urine you produce)
    • Lithium (a medicine used to treat some types of depression)
    • Potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium, and other substances that may increase potassium levels
    • Certain types of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) or selective cyclooxygenase-2 inhibitors (COX-2 inhibitors). Your doctor may also check your kidney function
    • Anticonvulsant agents (eg carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone)
    • St. John"s wort
    • Nitroglycerin and other nitrates, or other substances called "vasodilators"
    • Medicines used for HIV/AIDS (eg ritonavir, indinavir and nelfinavir)
    • Medicines used to treat fungal infections (eg ketoconazole, itraconazole)
    • Medicines used to treat bacterial infections (such as rifampicin, erythromycin, clarithromycin and talithromycin)
    • Verapamil, diltiazem (heart medications)
    • simvastatin (a medicine used to control high cholesterol levels)
    • Dantrolene (infusion in severe abnormalities of body temperature)
    • Medicines used to prevent transplant rejection (cyclosporine)
     
    Amlodipine/Valsartan with food and drink:
    Grapefruit and grapefruit juice should not be eaten by people who are taking amlodipine/valsartan. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active substance amlodipine, which could lead to an unexpected increase in the blood pressure lowering effect of amlodipine/valsartan.
     
    Pregnancy and lactation:
    pregnancy:
    You should tell your doctor if you think you are (or might become) pregnant. Your doctor will usually advise you to stop taking amlodipine/valsartan before you become pregnant or as soon as you know you are pregnant, and will advise you to take another medicine instead of amlodipine/valsartan. Amlodipine/valsartan is not recommended for use early in pregnancy (first trimester), and should not be taken after more than 3 months of pregnancy, as it may cause serious harm to your baby if used after the third month of pregnancy.
     
    Breastfeeding:
    Tell your doctor if you are breast-feeding or about to start breast-feeding. Amlodipine has been shown to pass into breast milk in small amounts. Amlodipine/Valsartan is not recommended for breastfeeding mothers, and your doctor may choose another treatment for you if you wish to breastfeed especially if your baby is a newborn or was born prematurely.
     
    Driving and using machines:
    This medicine makes you dizzy and loses your ability to focus. Therefore, if you are not sure how this medicine will affect you, do not drive, use machinery, or do other activities that need to be focused.
     
    How to take amlodipine/valsartan:
    The usual dose of amlodipine/valsartan is one tablet per day.
    It is best to take your medicine at the same time each day.
    Swallow the tablets with a glass of water.
    You can take amlodipine/valsartan with or without food. Do not take amlodipine/valsartan with grapefruit or grapefruit juice.
    Depending on how you respond to treatment, your doctor may suggest a higher or lower dose. Do not exceed the prescribed dose.
    Amlodipine/valsartan and the elderly (65 years or older)
    Your doctor should use caution when increasing your dose.
     
    If you take more amlodipine/valsartan than you should:
    If you take too many amlodipine/valsartan tablets, or if someone else takes your tablets, check with your doctor right away.
     
    If you forget to take amlodipine/valsartan:
    If you forget to take this medicine, take it as soon as you remember. Then take your next dose at the usual time. However, if it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten tablet.
     
    If you stop taking amlodipine/valsartan:
    Stopping treatment with amlodipine/valsartan may worsen your disease. Do not stop taking your medication unless your doctor tells you to.
     
    Possible side effects:
    Like all medicines, this medicine can cause side effects, although not everybody gets them.
     
    Some side effects can be serious and need immediate medical attention:
    A small number of patients have experienced these serious side effects (they may affect up to 1 in 1,000 people).
     
    If any of the following occur, tell your doctor right away:
    Allergic reaction accompanied by symptoms such as rash, itching, swelling of the face, lips or tongue, difficulty breathing, low blood pressure (feeling faint, light-headedness).
     
    Other possible side effects of amlodipine/valsartan:
    Common (may affect up to 1 in 10 people): Influenza. stuffy nose, sore throat, discomfort when swallowing; Headache; Swelling of the arms, hands, legs, ankles or feet. Tired. Asthenia (weakness) Redness and a warm feeling in the face and/or neck.
     
    Uncommon (may affect up to 1 in 100 people): Dizziness. Nausea and abdominal pain. dry mouth; drowsiness, tingling or numbness in the hands or feet; Dizziness, fast heartbeat, including palpitations. dizziness upon standing cough; Diarrhea; Constipation; Skin rash and redness. Joint swelling and back pain. pain in the joints.
     
    Side effects reported with amlodipine or valsartan alone and either not seen with amlodipine/valsartan or observed with a higher frequency than with amlodipine/valsartan:
    Amlodipine:
    Consult your doctor immediately if you experience any of the following very rare severe side effects after taking this medicine:
    • Sudden wheezing, chest pain, shortness of breath or difficulty breathing.
    • Swelling of the eyelids, face or lips.
    • Swelling of the tongue and throat, which causes great difficulty in breathing.
    • Severe skin reactions including severe rash, hives, redness of the skin all over the body, severe itching, blistering, peeling, swelling of the skin, inflammation of the mucous membranes (Stevens-Johnson syndrome, toxic epidermal necrolysis) or other allergic reactions.
    • Heart attack, irregular heartbeat.
    • Pancreatitis, which may cause severe abdominal and back pain accompanied by feeling very unwell.
     
    Common (may affect up to 1 in 10 people)
    dizziness, drowsiness; palpitations (perception of your heartbeat); redness, swelling of the ankle (oedema); Abdominal pain, feeling sick (nausea).
     
    Uncommon (may affect up to 1 in 100 people)
    Mood changes, anxiety, depression, insomnia, tremors, taste abnormalities, fainting, loss of sensation of pain. Visual disturbances, visual impairment and ringing in the ears. low blood pressure; sneezing/runny nose caused by inflammation of the lining of the nose (rhinitis); indigestion and vomiting (illness); Hair loss, increased sweating, itchy skin, skin discoloration. disturbance of urination, increased need to urinate at night, increased frequency of urination; erectile dysfunction, discomfort, or enlarged breasts in men, pain, feeling unwell, muscle aches, muscle cramps; Weight gain or loss.
     
    Valsartan:
    Unknown (frequency cannot be estimated from the available data)
    A decrease in red blood cells, fever, sore throat or mouth sores due to infections. Spontaneous bleeding or bruising. High level of potassium in the blood. Abnormal liver test results. Decreased renal function and severely decreased renal function. Swelling mainly in the face and throat. muscle pain; Skin rash, red-purple spots. Fever; itchy; allergic reaction; sores on the skin (a sign of a condition called bullous dermatitis).
     
    How to store amlodipine/valsartan:
    Keep this medicine out of the sight and reach of children.
     
    pharmacy :
    Online Pharmacy - Taj Al Dawaa Pharmacy.
     
    Trade Name:
    Lotevan 10/ 160 mg Tablet 30.
     
    The scientific name:
    Amlodipine/Valsartan 10 mg/160 mg Film Coated Tablets/Amlodipine (Amlodipine Besylate).
     
    Category:
     
    For more information about Lotevan 10/ 160 mg Tablet 30, please visit the Saudi Food and Drug Authority website.
    A valid prescription must be presented upon receipt of the order.
     
    What is amlodipine/valsartan and what is it used for?
    Amlodipine/Valsartan tablets contain two substances called amlodipine and valsartan. These two substances help control high blood pressure.
    Amlodipine belongs to a group of substances called "calcium channel blockers". Amlodipine prevents calcium from moving into the blood vessel wall, which prevents the blood vessels from narrowing.
    Valsartan belongs to a group of substances called "angiotensin II receptor antagonists". The body produces angiotensin II and makes the blood vessels narrow, thus increasing blood pressure. Valsartan works by blocking the effect of angiotensin II.
    This means that both of these substances help stop the tightening of blood vessels. As a result, blood vessels relax and blood pressure drops.
    Amlodipine/valsartan is used to treat high blood pressure in adults whose blood pressure is not adequately controlled with amlodipine or valsartan alone.
     
    What you should know before taking amlodipine/valsartan?
    Do not take amlodipine/valsartan:
    • If you are allergic to amlodipine or any other calcium channel blocker. This may include itching, redness of the skin, or trouble breathing.
    • If you are allergic to valsartan or any of the other ingredients of this medicine. If you think you may be allergic, talk to your doctor before taking amlodipine/valsartan.
    • If you suffer from serious liver problems or bile problems such as cirrhosis of the liver or cholestasis.
    • If you are more than 3 months pregnant. (It is also best to avoid amlodipine/valsartan in early pregnancy.)
    • If you suffer from a severe drop in blood pressure (hypotension).
    • If you have narrowing of the aortic valve (aortic stenosis) or cardiogenic shock (a condition in which your heart is unable to supply the body with enough blood).
    • If you suffer from heart failure after a heart attack.
    • If you suffer from diabetes or poor kidney function and are being treated with a medicine to lower blood pressure that contains aliskiren.
     
    Warnings and precautions:
    Talk to your doctor before taking amlodipine/valsartan:
    • If you are sick (vomiting or diarrhoea).
    • If you suffer from liver or kidney problems.
    • If you have had a kidney transplant or if you have been told you have narrowed kidney arteries.
    • If you have a condition affecting the renal glands called "primary hyperaldosteronism".
    • If you suffer from heart failure or a heart attack. Follow your doctor"s instructions for the starting dose carefully. Your doctor may also check your kidney function.
    • If your doctor tells you that you have narrowing of the valves in your heart (called "aortic stenosis or mitral valve") or that the heart muscle is abnormally thickened (called "hypertrophic obstructive cardiomyopathy").
    • If you experience swelling, especially of the face and throat, while taking other medicines (including ACE inhibitors). If you develop these symptoms, stop taking amlodipine/valsartan and call your doctor at once. You should not take amlodipine/valsartan again.
     
    If you are taking any of the following medicines used to treat high blood pressure:
    • ACE inhibitors (eg enalapril, lisinopril, ramipril), especially if you have diabetes-related kidney problems.
    • Aliskiren.
     
    Children and teens:
     
    Amlodipine/valsartan is not recommended for use in children and adolescents (under 18 years of age).
     
    Other medicines and amlodipine/valsartan:
    Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Your doctor may need to change your dose and/or take other precautions. In some cases, you may have to stop taking one of the medicines. This is especially true for the medicines listed below:
    • Angiotensin converting enzyme inhibitors or aliskiren
    Diuretics (a type of medicine also called "water tablets" that increase the amount of urine you produce)
    • Lithium (a medicine used to treat some types of depression)
    • Potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium, and other substances that may increase potassium levels
    • Certain types of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) or selective cyclooxygenase-2 inhibitors (COX-2 inhibitors). Your doctor may also check your kidney function
    • Anticonvulsant agents (eg carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone)
    • St. John"s wort
    • Nitroglycerin and other nitrates, or other substances called "vasodilators"
    • Medicines used for HIV/AIDS (eg ritonavir, indinavir and nelfinavir)
    • Medicines used to treat fungal infections (eg ketoconazole, itraconazole)
    • Medicines used to treat bacterial infections (such as rifampicin, erythromycin, clarithromycin and talithromycin)
    • Verapamil, diltiazem (heart medications)
    • simvastatin (a medicine used to control high cholesterol levels)
    • Dantrolene (infusion in severe abnormalities of body temperature)
    • Medicines used to prevent transplant rejection (cyclosporine)
     
    Amlodipine/Valsartan with food and drink:
    Grapefruit and grapefruit juice should not be eaten by people who are taking amlodipine/valsartan. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active substance amlodipine, which could lead to an unexpected increase in the blood pressure lowering effect of amlodipine/valsartan.
     
    Pregnancy and lactation:
    pregnancy:
    You should tell your doctor if you think you are (or might become) pregnant. Your doctor will usually advise you to stop taking amlodipine/valsartan before you become pregnant or as soon as you know you are pregnant, and will advise you to take another medicine instead of amlodipine/valsartan. Amlodipine/valsartan is not recommended for use early in pregnancy (first trimester), and should not be taken after more than 3 months of pregnancy, as it may cause serious harm to your baby if used after the third month of pregnancy.
     
    Breastfeeding:
    Tell your doctor if you are breast-feeding or about to start breast-feeding. Amlodipine has been shown to pass into breast milk in small amounts. Amlodipine/Valsartan is not recommended for breastfeeding mothers, and your doctor may choose another treatment for you if you wish to breastfeed especially if your baby is a newborn or was born prematurely.
     
    Driving and using machines:
    This medicine makes you dizzy and loses your ability to focus. Therefore, if you are not sure how this medicine will affect you, do not drive, use machinery, or do other activities that need to be focused.
     
    How to take amlodipine/valsartan:
    The usual dose of amlodipine/valsartan is one tablet per day.
    It is best to take your medicine at the same time each day.
    Swallow the tablets with a glass of water.
    You can take amlodipine/valsartan with or without food. Do not take amlodipine/valsartan with grapefruit or grapefruit juice.
    Depending on how you respond to treatment, your doctor may suggest a higher or lower dose. Do not exceed the prescribed dose.
    Amlodipine/valsartan and the elderly (65 years or older)
    Your doctor should use caution when increasing your dose.
     
    If you take more amlodipine/valsartan than you should:
    If you take too many amlodipine/valsartan tablets, or if someone else takes your tablets, check with your doctor right away.
     
    If you forget to take amlodipine/valsartan:
    If you forget to take this medicine, take it as soon as you remember. Then take your next dose at the usual time. However, if it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten tablet.
     
    If you stop taking amlodipine/valsartan:
    Stopping treatment with amlodipine/valsartan may worsen your disease. Do not stop taking your medication unless your doctor tells you to.
     
    Possible side effects:
    Like all medicines, this medicine can cause side effects, although not everybody gets them.
     
    Some side effects can be serious and need immediate medical attention:
    A small number of patients have experienced these serious side effects (they may affect up to 1 in 1,000 people).
     
    If any of the following occur, tell your doctor right away:
    Allergic reaction accompanied by symptoms such as rash, itching, swelling of the face, lips or tongue, difficulty breathing, low blood pressure (feeling faint, light-headedness).
     
    Other possible side effects of amlodipine/valsartan:
    Common (may affect up to 1 in 10 people): Influenza. stuffy nose, sore throat, discomfort when swallowing; Headache; Swelling of the arms, hands, legs, ankles or feet. Tired. Asthenia (weakness) Redness and a warm feeling in the face and/or neck.
     
    Uncommon (may affect up to 1 in 100 people): Dizziness. Nausea and abdominal pain. dry mouth; drowsiness, tingling or numbness in the hands or feet; Dizziness, fast heartbeat, including palpitations. dizziness upon standing cough; Diarrhea; Constipation; Skin rash and redness. Joint swelling and back pain. pain in the joints.
     
    Side effects reported with amlodipine or valsartan alone and either not seen with amlodipine/valsartan or observed with a higher frequency than with amlodipine/valsartan:
    Amlodipine:
    Consult your doctor immediately if you experience any of the following very rare severe side effects after taking this medicine:
    • Sudden wheezing, chest pain, shortness of breath or difficulty breathing.
    • Swelling of the eyelids, face or lips.
    • Swelling of the tongue and throat, which causes great difficulty in breathing.
    • Severe skin reactions including severe rash, hives, redness of the skin all over the body, severe itching, blistering, peeling, swelling of the skin, inflammation of the mucous membranes (Stevens-Johnson syndrome, toxic epidermal necrolysis) or other allergic reactions.
    • Heart attack, irregular heartbeat.
    • Pancreatitis, which may cause severe abdominal and back pain accompanied by feeling very unwell.
     
    Common (may affect up to 1 in 10 people)
    dizziness, drowsiness; palpitations (perception of your heartbeat); redness, swelling of the ankle (oedema); Abdominal pain, feeling sick (nausea).
     
    Uncommon (may affect up to 1 in 100 people)
    Mood changes, anxiety, depression, insomnia, tremors, taste abnormalities, fainting, loss of sensation of pain. Visual disturbances, visual impairment and ringing in the ears. low blood pressure; sneezing/runny nose caused by inflammation of the lining of the nose (rhinitis); indigestion and vomiting (illness); Hair loss, increased sweating, itchy skin, skin discoloration. disturbance of urination, increased need to urinate at night, increased frequency of urination; erectile dysfunction, discomfort, or enlarged breasts in men, pain, feeling unwell, muscle aches, muscle cramps; Weight gain or loss.
     
    Valsartan:
    Unknown (frequency cannot be estimated from the available data)
    A decrease in red blood cells, fever, sore throat or mouth sores due to infections. Spontaneous bleeding or bruising. High level of potassium in the blood. Abnormal liver test results. Decreased renal function and severely decreased renal function. Swelling mainly in the face and throat. muscle pain; Skin rash, red-purple spots. Fever; itchy; allergic reaction; sores on the skin (a sign of a condition called bullous dermatitis).
     
    How to store amlodipine/valsartan:
    Keep this medicine out of the sight and reach of children.
     
    pharmacy :
    Online Pharmacy - Taj Al Dawaa Pharmacy.
     
    Trade Name:
    Lotevan 10/ 160 mg Tablet 30.
     
    The scientific name:
    Amlodipine/Valsartan 10 mg/160 mg Film Coated Tablets/Amlodipine (Amlodipine Besylate).
     
    Category:
     
    For more information about Lotevan 10/ 160 mg Tablet 30, please visit the Saudi Food and Drug Authority website.

    About the product

    A valid prescription must be presented upon receipt of the order.
     
    What is amlodipine/valsartan and what is it used for?
    Amlodipine/Valsartan tablets contain two substances called amlodipine and valsartan. These two substances help control high blood pressure.
    Amlodipine belongs to a group of substances called "calcium channel blockers". Amlodipine prevents calcium from moving into the blood vessel wall, which prevents the blood vessels from narrowing.
    Valsartan belongs to a group of substances called "angiotensin II receptor antagonists". The body produces angiotensin II and makes the blood vessels narrow, thus increasing blood pressure. Valsartan works by blocking the effect of angiotensin II.
    This means that both of these substances help stop the tightening of blood vessels. As a result, blood vessels relax and blood pressure drops.
    Amlodipine/valsartan is used to treat high blood pressure in adults whose blood pressure is not adequately controlled with amlodipine or valsartan alone.
     
    What you should know before taking amlodipine/valsartan?
    Do not take amlodipine/valsartan:
    • If you are allergic to amlodipine or any other calcium channel blocker. This may include itching, redness of the skin, or trouble breathing.
    • If you are allergic to valsartan or any of the other ingredients of this medicine. If you think you may be allergic, talk to your doctor before taking amlodipine/valsartan.
    • If you suffer from serious liver problems or bile problems such as cirrhosis of the liver or cholestasis.
    • If you are more than 3 months pregnant. (It is also best to avoid amlodipine/valsartan in early pregnancy.)
    • If you suffer from a severe drop in blood pressure (hypotension).
    • If you have narrowing of the aortic valve (aortic stenosis) or cardiogenic shock (a condition in which your heart is unable to supply the body with enough blood).
    • If you suffer from heart failure after a heart attack.
    • If you suffer from diabetes or poor kidney function and are being treated with a medicine to lower blood pressure that contains aliskiren.
     
    Warnings and precautions:
    Talk to your doctor before taking amlodipine/valsartan:
    • If you are sick (vomiting or diarrhoea).
    • If you suffer from liver or kidney problems.
    • If you have had a kidney transplant or if you have been told you have narrowed kidney arteries.
    • If you have a condition affecting the renal glands called "primary hyperaldosteronism".
    • If you suffer from heart failure or a heart attack. Follow your doctor"s instructions for the starting dose carefully. Your doctor may also check your kidney function.
    • If your doctor tells you that you have narrowing of the valves in your heart (called "aortic stenosis or mitral valve") or that the heart muscle is abnormally thickened (called "hypertrophic obstructive cardiomyopathy").
    • If you experience swelling, especially of the face and throat, while taking other medicines (including ACE inhibitors). If you develop these symptoms, stop taking amlodipine/valsartan and call your doctor at once. You should not take amlodipine/valsartan again.
     
    If you are taking any of the following medicines used to treat high blood pressure:
    • ACE inhibitors (eg enalapril, lisinopril, ramipril), especially if you have diabetes-related kidney problems.
    • Aliskiren.
     
    Children and teens:
     
    Amlodipine/valsartan is not recommended for use in children and adolescents (under 18 years of age).
     
    Other medicines and amlodipine/valsartan:
    Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Your doctor may need to change your dose and/or take other precautions. In some cases, you may have to stop taking one of the medicines. This is especially true for the medicines listed below:
    • Angiotensin converting enzyme inhibitors or aliskiren
    Diuretics (a type of medicine also called "water tablets" that increase the amount of urine you produce)
    • Lithium (a medicine used to treat some types of depression)
    • Potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium, and other substances that may increase potassium levels
    • Certain types of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) or selective cyclooxygenase-2 inhibitors (COX-2 inhibitors). Your doctor may also check your kidney function
    • Anticonvulsant agents (eg carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone)
    • St. John"s wort
    • Nitroglycerin and other nitrates, or other substances called "vasodilators"
    • Medicines used for HIV/AIDS (eg ritonavir, indinavir and nelfinavir)
    • Medicines used to treat fungal infections (eg ketoconazole, itraconazole)
    • Medicines used to treat bacterial infections (such as rifampicin, erythromycin, clarithromycin and talithromycin)
    • Verapamil, diltiazem (heart medications)
    • simvastatin (a medicine used to control high cholesterol levels)
    • Dantrolene (infusion in severe abnormalities of body temperature)
    • Medicines used to prevent transplant rejection (cyclosporine)
     
    Amlodipine/Valsartan with food and drink:
    Grapefruit and grapefruit juice should not be eaten by people who are taking amlodipine/valsartan. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active substance amlodipine, which could lead to an unexpected increase in the blood pressure lowering effect of amlodipine/valsartan.
     
    Pregnancy and lactation:
    pregnancy:
    You should tell your doctor if you think you are (or might become) pregnant. Your doctor will usually advise you to stop taking amlodipine/valsartan before you become pregnant or as soon as you know you are pregnant, and will advise you to take another medicine instead of amlodipine/valsartan. Amlodipine/valsartan is not recommended for use early in pregnancy (first trimester), and should not be taken after more than 3 months of pregnancy, as it may cause serious harm to your baby if used after the third month of pregnancy.
     
    Breastfeeding:
    Tell your doctor if you are breast-feeding or about to start breast-feeding. Amlodipine has been shown to pass into breast milk in small amounts. Amlodipine/Valsartan is not recommended for breastfeeding mothers, and your doctor may choose another treatment for you if you wish to breastfeed especially if your baby is a newborn or was born prematurely.
     
    Driving and using machines:
    This medicine makes you dizzy and loses your ability to focus. Therefore, if you are not sure how this medicine will affect you, do not drive, use machinery, or do other activities that need to be focused.
     
    How to take amlodipine/valsartan:
    The usual dose of amlodipine/valsartan is one tablet per day.
    It is best to take your medicine at the same time each day.
    Swallow the tablets with a glass of water.
    You can take amlodipine/valsartan with or without food. Do not take amlodipine/valsartan with grapefruit or grapefruit juice.
    Depending on how you respond to treatment, your doctor may suggest a higher or lower dose. Do not exceed the prescribed dose.
    Amlodipine/valsartan and the elderly (65 years or older)
    Your doctor should use caution when increasing your dose.
     
    If you take more amlodipine/valsartan than you should:
    If you take too many amlodipine/valsartan tablets, or if someone else takes your tablets, check with your doctor right away.
     
    If you forget to take amlodipine/valsartan:
    If you forget to take this medicine, take it as soon as you remember. Then take your next dose at the usual time. However, if it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten tablet.
     
    If you stop taking amlodipine/valsartan:
    Stopping treatment with amlodipine/valsartan may worsen your disease. Do not stop taking your medication unless your doctor tells you to.
     
    Possible side effects:
    Like all medicines, this medicine can cause side effects, although not everybody gets them.
     
    Some side effects can be serious and need immediate medical attention:
    A small number of patients have experienced these serious side effects (they may affect up to 1 in 1,000 people).
     
    If any of the following occur, tell your doctor right away:
    Allergic reaction accompanied by symptoms such as rash, itching, swelling of the face, lips or tongue, difficulty breathing, low blood pressure (feeling faint, light-headedness).
     
    Other possible side effects of amlodipine/valsartan:
    Common (may affect up to 1 in 10 people): Influenza. stuffy nose, sore throat, discomfort when swallowing; Headache; Swelling of the arms, hands, legs, ankles or feet. Tired. Asthenia (weakness) Redness and a warm feeling in the face and/or neck.
     
    Uncommon (may affect up to 1 in 100 people): Dizziness. Nausea and abdominal pain. dry mouth; drowsiness, tingling or numbness in the hands or feet; Dizziness, fast heartbeat, including palpitations. dizziness upon standing cough; Diarrhea; Constipation; Skin rash and redness. Joint swelling and back pain. pain in the joints.
     
    Side effects reported with amlodipine or valsartan alone and either not seen with amlodipine/valsartan or observed with a higher frequency than with amlodipine/valsartan:
    Amlodipine:
    Consult your doctor immediately if you experience any of the following very rare severe side effects after taking this medicine:
    • Sudden wheezing, chest pain, shortness of breath or difficulty breathing.
    • Swelling of the eyelids, face or lips.
    • Swelling of the tongue and throat, which causes great difficulty in breathing.
    • Severe skin reactions including severe rash, hives, redness of the skin all over the body, severe itching, blistering, peeling, swelling of the skin, inflammation of the mucous membranes (Stevens-Johnson syndrome, toxic epidermal necrolysis) or other allergic reactions.
    • Heart attack, irregular heartbeat.
    • Pancreatitis, which may cause severe abdominal and back pain accompanied by feeling very unwell.
     
    Common (may affect up to 1 in 10 people)
    dizziness, drowsiness; palpitations (perception of your heartbeat); redness, swelling of the ankle (oedema); Abdominal pain, feeling sick (nausea).
     
    Uncommon (may affect up to 1 in 100 people)
    Mood changes, anxiety, depression, insomnia, tremors, taste abnormalities, fainting, loss of sensation of pain. Visual disturbances, visual impairment and ringing in the ears. low blood pressure; sneezing/runny nose caused by inflammation of the lining of the nose (rhinitis); indigestion and vomiting (illness); Hair loss, increased sweating, itchy skin, skin discoloration. disturbance of urination, increased need to urinate at night, increased frequency of urination; erectile dysfunction, discomfort, or enlarged breasts in men, pain, feeling unwell, muscle aches, muscle cramps; Weight gain or loss.
     
    Valsartan:
    Unknown (frequency cannot be estimated from the available data)
    A decrease in red blood cells, fever, sore throat or mouth sores due to infections. Spontaneous bleeding or bruising. High level of potassium in the blood. Abnormal liver test results. Decreased renal function and severely decreased renal function. Swelling mainly in the face and throat. muscle pain; Skin rash, red-purple spots. Fever; itchy; allergic reaction; sores on the skin (a sign of a condition called bullous dermatitis).
     
    How to store amlodipine/valsartan:
    Keep this medicine out of the sight and reach of children.
     
    pharmacy :
    Online Pharmacy - Taj Al Dawaa Pharmacy.
     
    Trade Name:
    Lotevan 10/ 160 mg Tablet 30.
     
    The scientific name:
    Amlodipine/Valsartan 10 mg/160 mg Film Coated Tablets/Amlodipine (Amlodipine Besylate).
     
    Category:
     
    For more information about Lotevan 10/ 160 mg Tablet 30, please visit the Saudi Food and Drug Authority website.

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    A valid prescription must be presented upon receipt of the order.
     
    What is amlodipine/valsartan and what is it used for?
    Amlodipine/Valsartan tablets contain two substances called amlodipine and valsartan. These two substances help control high blood pressure.
    Amlodipine belongs to a group of substances called "calcium channel blockers". Amlodipine prevents calcium from moving into the blood vessel wall, which prevents the blood vessels from narrowing.
    Valsartan belongs to a group of substances called "angiotensin II receptor antagonists". The body produces angiotensin II and makes the blood vessels narrow, thus increasing blood pressure. Valsartan works by blocking the effect of angiotensin II.
    This means that both of these substances help stop the tightening of blood vessels. As a result, blood vessels relax and blood pressure drops.
    Amlodipine/valsartan is used to treat high blood pressure in adults whose blood pressure is not adequately controlled with amlodipine or valsartan alone.
     
    What you should know before taking amlodipine/valsartan?
    Do not take amlodipine/valsartan:
    • If you are allergic to amlodipine or any other calcium channel blocker. This may include itching, redness of the skin, or trouble breathing.
    • If you are allergic to valsartan or any of the other ingredients of this medicine. If you think you may be allergic, talk to your doctor before taking amlodipine/valsartan.
    • If you suffer from serious liver problems or bile problems such as cirrhosis of the liver or cholestasis.
    • If you are more than 3 months pregnant. (It is also best to avoid amlodipine/valsartan in early pregnancy.)
    • If you suffer from a severe drop in blood pressure (hypotension).
    • If you have narrowing of the aortic valve (aortic stenosis) or cardiogenic shock (a condition in which your heart is unable to supply the body with enough blood).
    • If you suffer from heart failure after a heart attack.
    • If you suffer from diabetes or poor kidney function and are being treated with a medicine to lower blood pressure that contains aliskiren.
     
    Warnings and precautions:
    Talk to your doctor before taking amlodipine/valsartan:
    • If you are sick (vomiting or diarrhoea).
    • If you suffer from liver or kidney problems.
    • If you have had a kidney transplant or if you have been told you have narrowed kidney arteries.
    • If you have a condition affecting the renal glands called "primary hyperaldosteronism".
    • If you suffer from heart failure or a heart attack. Follow your doctor"s instructions for the starting dose carefully. Your doctor may also check your kidney function.
    • If your doctor tells you that you have narrowing of the valves in your heart (called "aortic stenosis or mitral valve") or that the heart muscle is abnormally thickened (called "hypertrophic obstructive cardiomyopathy").
    • If you experience swelling, especially of the face and throat, while taking other medicines (including ACE inhibitors). If you develop these symptoms, stop taking amlodipine/valsartan and call your doctor at once. You should not take amlodipine/valsartan again.
     
    If you are taking any of the following medicines used to treat high blood pressure:
    • ACE inhibitors (eg enalapril, lisinopril, ramipril), especially if you have diabetes-related kidney problems.
    • Aliskiren.
     
    Children and teens:
     
    Amlodipine/valsartan is not recommended for use in children and adolescents (under 18 years of age).
     
    Other medicines and amlodipine/valsartan:
    Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Your doctor may need to change your dose and/or take other precautions. In some cases, you may have to stop taking one of the medicines. This is especially true for the medicines listed below:
    • Angiotensin converting enzyme inhibitors or aliskiren
    Diuretics (a type of medicine also called "water tablets" that increase the amount of urine you produce)
    • Lithium (a medicine used to treat some types of depression)
    • Potassium-sparing diuretics, potassium supplements, salt substitutes containing potassium, and other substances that may increase potassium levels
    • Certain types of painkillers called nonsteroidal anti-inflammatory drugs (NSAIDs) or selective cyclooxygenase-2 inhibitors (COX-2 inhibitors). Your doctor may also check your kidney function
    • Anticonvulsant agents (eg carbamazepine, phenobarbital, phenytoin, fosphenytoin, primidone)
    • St. John"s wort
    • Nitroglycerin and other nitrates, or other substances called "vasodilators"
    • Medicines used for HIV/AIDS (eg ritonavir, indinavir and nelfinavir)
    • Medicines used to treat fungal infections (eg ketoconazole, itraconazole)
    • Medicines used to treat bacterial infections (such as rifampicin, erythromycin, clarithromycin and talithromycin)
    • Verapamil, diltiazem (heart medications)
    • simvastatin (a medicine used to control high cholesterol levels)
    • Dantrolene (infusion in severe abnormalities of body temperature)
    • Medicines used to prevent transplant rejection (cyclosporine)
     
    Amlodipine/Valsartan with food and drink:
    Grapefruit and grapefruit juice should not be eaten by people who are taking amlodipine/valsartan. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active substance amlodipine, which could lead to an unexpected increase in the blood pressure lowering effect of amlodipine/valsartan.
     
    Pregnancy and lactation:
    pregnancy:
    You should tell your doctor if you think you are (or might become) pregnant. Your doctor will usually advise you to stop taking amlodipine/valsartan before you become pregnant or as soon as you know you are pregnant, and will advise you to take another medicine instead of amlodipine/valsartan. Amlodipine/valsartan is not recommended for use early in pregnancy (first trimester), and should not be taken after more than 3 months of pregnancy, as it may cause serious harm to your baby if used after the third month of pregnancy.
     
    Breastfeeding:
    Tell your doctor if you are breast-feeding or about to start breast-feeding. Amlodipine has been shown to pass into breast milk in small amounts. Amlodipine/Valsartan is not recommended for breastfeeding mothers, and your doctor may choose another treatment for you if you wish to breastfeed especially if your baby is a newborn or was born prematurely.
     
    Driving and using machines:
    This medicine makes you dizzy and loses your ability to focus. Therefore, if you are not sure how this medicine will affect you, do not drive, use machinery, or do other activities that need to be focused.
     
    How to take amlodipine/valsartan:
    The usual dose of amlodipine/valsartan is one tablet per day.
    It is best to take your medicine at the same time each day.
    Swallow the tablets with a glass of water.
    You can take amlodipine/valsartan with or without food. Do not take amlodipine/valsartan with grapefruit or grapefruit juice.
    Depending on how you respond to treatment, your doctor may suggest a higher or lower dose. Do not exceed the prescribed dose.
    Amlodipine/valsartan and the elderly (65 years or older)
    Your doctor should use caution when increasing your dose.
     
    If you take more amlodipine/valsartan than you should:
    If you take too many amlodipine/valsartan tablets, or if someone else takes your tablets, check with your doctor right away.
     
    If you forget to take amlodipine/valsartan:
    If you forget to take this medicine, take it as soon as you remember. Then take your next dose at the usual time. However, if it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten tablet.
     
    If you stop taking amlodipine/valsartan:
    Stopping treatment with amlodipine/valsartan may worsen your disease. Do not stop taking your medication unless your doctor tells you to.
     
    Possible side effects:
    Like all medicines, this medicine can cause side effects, although not everybody gets them.
     
    Some side effects can be serious and need immediate medical attention:
    A small number of patients have experienced these serious side effects (they may affect up to 1 in 1,000 people).
     
    If any of the following occur, tell your doctor right away:
    Allergic reaction accompanied by symptoms such as rash, itching, swelling of the face, lips or tongue, difficulty breathing, low blood pressure (feeling faint, light-headedness).
     
    Other possible side effects of amlodipine/valsartan:
    Common (may affect up to 1 in 10 people): Influenza. stuffy nose, sore throat, discomfort when swallowing; Headache; Swelling of the arms, hands, legs, ankles or feet. Tired. Asthenia (weakness) Redness and a warm feeling in the face and/or neck.
     
    Uncommon (may affect up to 1 in 100 people): Dizziness. Nausea and abdominal pain. dry mouth; drowsiness, tingling or numbness in the hands or feet; Dizziness, fast heartbeat, including palpitations. dizziness upon standing cough; Diarrhea; Constipation; Skin rash and redness. Joint swelling and back pain. pain in the joints.
     
    Side effects reported with amlodipine or valsartan alone and either not seen with amlodipine/valsartan or observed with a higher frequency than with amlodipine/valsartan:
    Amlodipine:
    Consult your doctor immediately if you experience any of the following very rare severe side effects after taking this medicine:
    • Sudden wheezing, chest pain, shortness of breath or difficulty breathing.
    • Swelling of the eyelids, face or lips.
    • Swelling of the tongue and throat, which causes great difficulty in breathing.
    • Severe skin reactions including severe rash, hives, redness of the skin all over the body, severe itching, blistering, peeling, swelling of the skin, inflammation of the mucous membranes (Stevens-Johnson syndrome, toxic epidermal necrolysis) or other allergic reactions.
    • Heart attack, irregular heartbeat.
    • Pancreatitis, which may cause severe abdominal and back pain accompanied by feeling very unwell.
     
    Common (may affect up to 1 in 10 people)
    dizziness, drowsiness; palpitations (perception of your heartbeat); redness, swelling of the ankle (oedema); Abdominal pain, feeling sick (nausea).
     
    Uncommon (may affect up to 1 in 100 people)
    Mood changes, anxiety, depression, insomnia, tremors, taste abnormalities, fainting, loss of sensation of pain. Visual disturbances, visual impairment and ringing in the ears. low blood pressure; sneezing/runny nose caused by inflammation of the lining of the nose (rhinitis); indigestion and vomiting (illness); Hair loss, increased sweating, itchy skin, skin discoloration. disturbance of urination, increased need to urinate at night, increased frequency of urination; erectile dysfunction, discomfort, or enlarged breasts in men, pain, feeling unwell, muscle aches, muscle cramps; Weight gain or loss.
     
    Valsartan:
    Unknown (frequency cannot be estimated from the available data)
    A decrease in red blood cells, fever, sore throat or mouth sores due to infections. Spontaneous bleeding or bruising. High level of potassium in the blood. Abnormal liver test results. Decreased renal function and severely decreased renal function. Swelling mainly in the face and throat. muscle pain; Skin rash, red-purple spots. Fever; itchy; allergic reaction; sores on the skin (a sign of a condition called bullous dermatitis).
     
    How to store amlodipine/valsartan:
    Keep this medicine out of the sight and reach of children.
     
    pharmacy :
    Online Pharmacy - Taj Al Dawaa Pharmacy.
     
    Trade Name:
    Lotevan 10/ 160 mg Tablet 30.
     
    The scientific name:
    Amlodipine/Valsartan 10 mg/160 mg Film Coated Tablets/Amlodipine (Amlodipine Besylate).
     
    Category:
     
    For more information about Lotevan 10/ 160 mg Tablet 30, please visit the Saudi Food and Drug Authority website.
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