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Lisinopril belongs to a group of medicines called angiotensin-converting enzyme (ACE) inhibitors.
Lisinopril 20 mg Tablets
What is Lisinopril and what is it used for?
It can be used for the following conditions:
• To treat high blood pressure (hypertension).
• To treat heart failure.
• If you have recently had a heart attack (myocardial infarction).
• To treat kidney problems caused by type 2 diabetes in people with high blood pressure.
It works by causing blood vessels to widen. This helps lower blood pressure. It also makes it easier for your heart to pump blood to all parts of your body.
Do not take Lisinopril
• If you are allergic to lisinopril or any of the other ingredients of this medicine
• If you have ever had an allergic reaction to another ACE inhibitor medicine. An allergic reaction may have caused swelling of the hands, feet, ankles, face, lips, tongue, or throat. It may also have made it difficult to swallow or breathe (angioedema).
• If you have taken or are currently taking sacubitril/valsartan, a medicine used to treat a type of long-term (chronic) heart failure in adults, your risk of angioedema (rapid swelling under the skin in an area such as the throat) is increased.
• If a family member has had severe allergic reactions (angioedema) to ACE inhibitors or has had severe allergic reactions (angioedema) with no known cause.
• If you are more than 3 months pregnant.
• If you have diabetes or impaired kidney function and are being treated with a blood pressure-lowering medicine containing aliskiren.
Warnings and Precautions
Talk to your doctor or pharmacist before taking lisinopril if you:
• Have narrowing (stenosis) of the aorta (an artery in your heart) or narrowing of the heart valves (mitral valves).
• Have narrowing (stenosis) of the renal artery.
• Have thickening of the heart muscle (known as cardiomyopathy).
• Have blood vessel problems (collagen vascular disease).
• Have low blood pressure. You may notice this as dizziness or lightheadedness, especially when standing up.
• Have kidney problems or are on dialysis.
• Have liver problems.
• Have diabetes.
• Are taking any of the following medicines used to treat high blood pressure: angiotensin II receptor blockers (ARBs), aliskiren.
• Have recently had diarrhea or vomiting (sickness).
• You have high cholesterol levels and are undergoing a treatment called LDL apheresis.
• You are of black origin, as lisinopril may be less effective. You may also more easily experience the side effect of angioedema (a severe allergic reaction).
Possible side effects of lisinopril
Common side effects
• Headache.
• Feeling dizzy or lightheaded, especially if you stand up quickly.
• Diarrhea.
• A dry cough that doesn't go away.
• Sickness (vomiting).
• Kidney problems (shown in a blood test).
Other medicines and lisinopril
In particular, tell your doctor or pharmacist if you are taking any of the following medicines:
• Other medicines to help lower your blood pressure.
• Angiotensin II receptor blockers (ARBs) or aliskiren.
• Water pills (diuretics).
• Beta-blockers, such as atenolol and propranolol.
• Nitrate medications (for heart problems).
• Nonsteroidal anti-inflammatory drugs (NSAIDs), used to treat pain and arthritis.
• Aspirin (acetylsalicylic acid), if you take more than 3 grams each day.
• Medications for depression and mental health problems, including lithium.
• Potassium supplements (including salt substitutes), potassium-sparing diuretics, and other medications that can increase the amount of potassium in the blood (such as trimethoprim and cotrimoxazole for infections caused by bacteria; cyclosporine, an immunosuppressant used to prevent rejection of transplanted organs; and heparin, a blood-thinning medication used to prevent clots).
• Insulin or oral medications for diabetes.
• Medicines used to treat asthma.
• Medicines for nasal or sinus congestion, or other cold remedies (including those you can buy over the counter).
• Medicines to suppress the body's immune response (immunosuppressants).
• Allopurinol (for gout).
• Procainamide for heart rhythm problems.
• Medicines containing gold, such as sodium aurothiomalate, which can be given as an injection.
How to take lisinopril
Adults
Your dose depends on your medical condition and whether you are taking any other medications. Your doctor will tell you how many tablets to take each day. Consult your doctor or pharmacist if you are unsure.
• For high blood pressure: The recommended starting dose is 10 mg once a day. The usual long-term dose is 20 mg once a day.
• For heart failure: The recommended starting dose is 2.5 mg once a day. The long-term dose is 5 to 35 mg once a day.
• After a heart attack: The recommended starting dose is 5 mg within 24 hours of the attack and 5 mg one day later. The usual long-term dose is 10 mg once a day.
• For kidney problems caused by diabetes: The recommended dose is either 10 mg or 20 mg once a day. If you are elderly, have kidney problems, or are taking diuretics, your doctor may give you a lower dose than usual.
Use in children and adolescents (6 to 16 years) with high blood pressure
• This medicine is not recommended for children under 6 years of age or for children with severe kidney problems.
• Your doctor will determine the correct dose for your child. The dose depends on the child's body weight.
• For children weighing 20 kg or more
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